A DIY store in Hawick has been earmarked for closure.
It is among 10 stores in Scotland which have been listed by Restructuring company Hilco to close over the next 16 months.
The company bought the struggling chain in May for £1.
Within a Company Voluntary Arrangement Hilco aims to shut under-performing shops.
The company said it was unable to say how many staff were affected at its Scottish stores, but staff at closed stores will be redeployed within the business where possible.
Homebase chief executive Damian McGloughlin said: "Launching a CVA has been a difficult decision and one that we have not taken lightly.
"Homebase has been one of the most recognisable retail brands for almost 40 years, but the reality is we need to continue to take decisive action to address the under-performance of the business and deal with the burden of our cost base, as well as to protect thousands of jobs.
"The CVA is therefore an essential measure for the business to take and will enable us to refocus our operations and rebuild our offer for the years ahead."
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