Severe weather has swept across the Deep South in the United States, killing at least 20 people and damaging hundreds of homes from Louisiana into the Appalachian Mountains.

Many people spent part of early Monday sheltering in basements, cupboards and baths as sirens wailed to warn of possible tornadoes.

Chattanooga in Tennessee and several counties in north-west Georgia appeared to be particularly hard-hit.

A home damaged by a tornado
Rolanda Robinson calls family and friends from her brother’s damaged home in Monroe (Nicolas Galindo/The News-Star via AP)

Murray County Georgia Fire Chief Dewayne Bain told WAGA-TV that two mobile home parks were severely damaged, with five people killed and five others taken to hospital after a line of narrow line of storms left a five-mile-long path of destruction.

Another person was killed when a tree fell on a home in Cartersville, Georgia, the station reported.

At least 14 people were taken to hospital in Chattanooga, where search and rescue teams from at least 10 fire departments were going door-to-door responding to more than 300 emergency calls for help, the fire department said.

The storms blew onward through the night, causing flooding and mudslides in mountainous areas, and knocking out power for about 750,000 people in a 10-state swath ranging from Texas to Georgia up to West Virginia, according to poweroutages.us.

The National Weather Service tallied hundreds of reports of trees down across the region, including many that punctured roofs and downed power lines.

Several apparent tornadoes spun up in South Carolina, where dozens of homes appeared damaged in a line from Seneca to Clemson.

Emergency officials were working to open shelters in the North Carolina mountains, where up to five inches of rain fell in a few hours.

Damaged planes at Monroe Regional Airport
Damaged planes at Monroe Regional Airport (Monroe News Star/Greg Hilburn via AP)

In southern Mississippi on Sunday, one person killed was in Walthall County, two were killed in Lawrence County and three were killed in Jefferson Davis County, state Emergency Management Agency director Greg Michel said.

The deaths included a married couple – Lawrence County sheriff’s deputy, Robert Ainsworth, and a Walthall County Justice Court deputy clerk, Paula We, a Facebook post from the county sheriff’s office said.

Mississippi Governor Tate Reeves declared a state of emergency on Sunday night after he said several tornadoes had struck the state.

“This is not how anyone wants to celebrate Easter,” Mr Reeves said on Twitter.

“As we reflect on the death and resurrection on this Easter Sunday, we have faith that we will all rise together.”

The National Weather Service advised the storm front would blow into the mid-Atlantic states on Monday, bringing potential tornadoes, wind and hail.

News outlets reported downed trees, flooded streets and other damage in Alabama, Tennessee and Georgia.

Strong winds late on Sunday toppled power lines and blew trees on to several houses in Clarksdale, Mississippi, trapping some people inside, Mayor Chuck Espy said.

“I know these are some tough times and I’m just asking everyone to stay prayed up,” he said.

There were no immediate reports of serious injuries in Louisiana, even though the storm damaged between 200 and 300 homes in and around the city of Monroe, Mayor Jamie Mayo, told KNOE-TV.

Flights were cancelled at Monroe Regional Airport, where airport director Ron Phillips told the News-Star the storm caused up to 30 million dollars (£24 million) in damage to planes inside a hangar.

In Alabama, lightning struck the Shoals Creek Baptist Church in Priceville, damaging the roof and steeple, Morgan County Emergency Management Agency Eddie Hicks told AL.com.